PMPCA antibody

Catalog No. ABIN6572100

This Rabbit Polyclonal antibody specifically detects PMPCA in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PMPCA antibody (ABIN6572100)

Target: PMPCA (Peptidase (Mitochondrial Processing) alpha (PMPCA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMPCA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PMPCA Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PMPCA

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PMPCA

Target: PMPCA (Peptidase (Mitochondrial Processing) alpha (PMPCA))

Alternative Name: PMPCA

Background:

Synonyms: 1200002L24Rik,4933435E07Rik,Alpha MPP,Alpha-MPP,FLJ26258,Inositol polyphosphate 5 phosphatase, 72 kD,INPP5E,KIAA0123,MGC104197,MGC93916,Mitochondrial matrix processing protease, alpha subunit,mitochondrial processing peptidase subunit alpha,Mitochondrial-processing peptidase subunit alpha,MPPA,P 55,P-55,Peptidase (mitochondrial processing) alpha,pmpca,RP11-413M3.1,RP23-306D20.8,SCAR2

Background: The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2.

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 44kDa/58kDa

Gene ID: 23203

UniProt: Q10713

Pathways: Inositol Metabolic Process, SARS-CoV-2 Protein Interactome